Hollywood partygirls Paris Hilton and Lindsay Lohan have their daggers drawn and aimed at comedienne Chelsea Handler after the pull no punches host of E!’s Chelsea Lately made a number of biting remarks about the girls in an interview with gay magazine The Advocate last month.

“Well, Paris isn’t as lonely because she just sleeps with everybody, so that fills her up for a little bit-literally and metaphorically,” Chelsea giggled.

The author of Are You There Vodka? It’s Me, Chelsea also went in on labia-lovin’ lezzie Lindsay Lohan:

“Lindsay is so confused. It would be great if the whole thing with Samantha [Ronson] works, but I don’t think she knows what she is. She’s just young and not the sharpest tool in the shed.”

Paris and Lindsay have retailiated by launching an arsenal of words of their own against Chelsea, The National Enquirer claims.

“Paris is used to being bombarded with off-color remarks, but they’re usually provoked. Chelsea’s diss came out of left field and Paris is striking back by making catty remarks about Chelsea whenever she gets the chance.”

You can bet 22-year-old Lindsay isn’t taking Chelsea’s remarks lying down either.

“Lindsay is telling pals that people with inadequacies in their own sex lives are the ones who usually make ignorant assumptions about the sex lives of others.”