The Material Girl is in hot water with longtime pal designer Christian Audigier after spontaneously pulling the plug on their plans to launch a clothing line baring Madonna’s name.

Christian nearly hit the roof when he learned that after months of sweating over designs — which were approved by Madge — the “Borderline” hitmaker had changed her mind about diving into the world of colorful sketches and catwalks after her application to adopt an orphan was rejected by a family court judge in the African nation of Malawi.

The National Enquirer writes: “Outraged Audigier says Madonna agreed to sign contracts for the deal a month ago, but when the Malawi authorities nixed her plea to adopt a native daughter, the distraught star blew off her designer pal, saying she was ‘depressed…and not in the right frame of mind” to continue working on the collection.