Jennifer Aniston is headed to the small screen in a new late-night talk show that will co-star media mogul Oprah Winfrey, The Daily Express reported on Sunday.

The former Friends actress is set to produce and star alongside the Queen of Talk in a weekly broadcast on The Oprah Winfrey Network (OWN), a new channel set to premiere next year.

It was Jen’s friendship with comedienne Chelsea Handler — who fronts her own knee-slapping late-night series on E! — that inspired her to take on the project.

A tipster tattles: “Jen became fascinated with the format after spending time with Chelsea. When she saw Oprah she mentioned that it would be fun to do a chat show and Oprah seized the moment and suggested they front one together for her new network.”

Jennifer, who is said to have a $210 million fortune, is still negotiating her salary for the project.

“Her salary is yet to be determined. She is doing this for one reason only: She absolutely wants to do it.”