Oscar-winning actress Gwyneth Paltrow will sit down for revealing interview with Oprah Winfrey when the Queen of Talk returns to the airwaves for the 23rd season of Oprah this Fall.

“It’ll be Gwyneth’s first in-depth interview in quite some time,” a source tells Life & Style. “She may talk about the rumors of Madonna and Guy Ritchie’s split, as well as her own marriage.”

Oprah will also dig into the 35-year-old’s history of depressed.

“Nothing is off-limits with Oprah. Expect Oprah to go there.”