Ryan Reynolds is auctioning off tickets to the premiere of his film X-Men Origins: Wolverine – with proceeds benefiting the Michael J. Fox Foundation for Parkinson’s Research. Ryan plays Deadpool in the movie, appearing alongside star Hugh Jackman, who reprises his X-Men role as Wolverine.

One lucky bidder will have the opportunity to attend the premiere and sit near Ryan.

“I am proud to be a part of this team of dedicated and motivated people who are getting out there and making a difference,” Ryan said in a statement Monday. “The Michael J. Fox Foundation is doing whatever it takes to improve patients’ quality of life and deliver a cure to people living with PD, like my father.”

The superhero thriller, set to kick off the summer blockbuster season when it opens in theaters May 1, will premiere at the Mann’s Chinese Theater in Hollywood on Monday, April 28.

For more information on this auction, go to charitybuzz.com.

The 47-year-old actor will appear on an episode of The Oprah Winfrey Show airing Tuesday. The former Family Ties star was diagnosed with Parkinson’s in 1991, and disclosed his condition to the public in 1998. As the symptoms of the disease worsened he semi-retired from acting in 2000.

“And, so whatever you’re trying to do, you’ve got this 4-year-old and you’re… just trying to be patient and focus on what you need to do,” he explains to The Queen of Talk.

Nonetheless, Michael tells Oprah that he refuses to allow his life to be ruled by the disease.

“I’m a dad, I’m a husband, I’m an activist, I’m a writer and I’m just a student of the world,” he says. “This is one fact of my life, but it’s not the totality of my life. It doesn’t define me.”

On May 7, Michael J. Fox will host Michael J. Fox: Adventures of an Incurable Optimist, a television special featuring the actor speaking to people worldwide about the enduring strength of hope in his quest to promote and learn more about optimism and the human spirit.

The former Spin City star put his acting career on hold in 2000 after being diagnosed with Parkinson’s disease in 1998. The Michael J. Fox Foundation is now the world’s largest non-profit funder of Parkinson’s research.

“For everything this disease has taken, something with greater value has been given,” Fox says. “So, sure, it may be one step forward and two steps back, but after a time with Parkinson’s, I’ve learned that what is important is making that one step count.”

Michael J. Fox: Adventures of an Incurable Optimist airs Thursday, May 7 on ABC.

In the April issue of Good Housekeeping, available on newsstands March 10, Michael J. Fox is speaking out about some of things that have inspired him to keep living since revealing that he has Parkinson’s Disease ten years ago.

The former Family Ties star talks about how he was inspired by a famous cyclist who also struggled with serious disease. “Then, Lance Armstrong showed up, and I started talking to him; I saw all these people with cancer who followed him to Paris for the Tour de France, and I saw the difference he was making in their lives. That put it together for me…having it be not so much about me, but [my being] a vehicle for it.”

Michael has written a new memoir titled Always Looking Up. An exclusive preview in available in the new issue of G.H.

Alex P. Keaton’s coming back to the small screen! Michael J. Fox is up for a guest-spot on the critically-acclaimed FX series Rescue Me.

The veteran actor and outspoken stem-cell research advocate could join the show for several episodes as a love interest of Janet (Andrea Roth).

“No deal is done yet,” an FX spokesperson told Entertainment Weekly Monday.