Twins Knox and Vivienne may be the last two biological children for serial babymakers Brad Pitt and Angelina Jolie. After two tough pregnancies, the Oscar-winning actress has been advised that a third pregnancy could be potentially life-threatening.

“Her previous pregnancies ended with emergency caesarian secions. She’s been told that, at the least, she should not get pregnant for a year after her last deliver, and it would be safer if she did not get pregnant, ever,” an insider revealed in this week’s edition of OK! Magazine.

“Angelina is at risk of having a stroke or heart attack, and because she developed gestational diabetes, there is a high risk she’ll have it again, with the child being at risk for diabetes.”