South African screen siren Charlize Theron has backed out of the globetrotting thriller The Tourist — and fellow Oscar winner Angelina Jolie is now reportedly in discussions to replace her, industry spies tell The Hollywood Reporter.

No reason has been given for Charlize’s departure..

The Tourist is a remake of the 2005 French thriller Anthony Zimmer. The plot follows an American tourist traveling abroad who is seduced by a beautiful woman and becomes caught in an international plot involving Interpol and the Russian mafia who both mistake him for a criminal mastermind.

Sam Worthington, of Terminator: Salvation and Avatar, has already signed on to play the male lead.

The Tourist is slated to begin shooting in early 2010.