Respected CNN anchor Anderson Cooper is feeling the wrath of Lohan after making several sharp remarks about the Long Island clan while sitting in for Regis Philbin on Live With Regis & Kelly on Tuesday.

“Living Lohan is just atrocious,” said Anderson, who branded the showbusiness family “horrific.”

“I cannot believe I’m wasting a minute of my life watching these horrific people,” Anderson retorted.

Even young Ali Lohan wasn’t safe from one of Andy’s quips:

“[Ali] is a 14-year-old girl, looks to be about 60. She allegedly wants to be a singer and or actor-slash-performer of some sort, striptease person, I don’t know.”

Ouch..in all fairness though, Ali does look like a 40-year-old soccer mom…we’re just saying.

Family matriarch Dina Lohan has hit back, saying, “People are just cruel! This is bad karma for him.”